Baked Italian Turkey Subs

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My baked Italian turkey subs recipe is a total crowd pleaser. I mean, who can say no to a baked crusty bread sandwich overloaded with sharp cheddar cheese, mayo, smoked turkey, onion, and turkey pepperoni. The answer? Not me!

Hot and Cheesy Italian Turkey Subs

I love a good hearty supper with tons of flavor that doesn’t require a lot of work, especially at the end of a hot summer’s day! So today I’m showing you how to make this deliciously ooey gooey extra cheesy baked Italian turkey sub sandwich, perfect on its own or with a dipping side of pizza sauce.

The original inspiration for this hot and cheesy Italian turkey subs recipe came from my buddy, Stacey Little, over at Southern Bite. Years ago he shared his mama’s recipe for top to bottom turkey and cheese bread and it’s been a favorite ever since.

Luckily, these Italian turkey subs are so quick and easy to make. All you need to do is combine the sharp cheddar cheese and mayo and spread that on some crusty French bread. Then we add layers of smoked turkey slices, turkey pepperoni, and onion. Now, all it needs is to be wrapped in foil and baked in the oven until it’s nice and toasted. 6 ingredients, 30 minutes, and dinner is served. Music to my ears!

Now, I don’t know about you, but we will be enjoying this quick summer supper with a big old glass of iced sweet tea, also made in a jiff! It’s the Southern way, after all.

Recipe Ingredients

  • Crusty french bread
  • Thinly sliced onion
  • Smoked turkey (from the deli)
  • Mayo
  • Shredded cheddar cheese
  • Pepperoni
  • Pizza sauce for dipping, if you like (totally optional).

How to Make Italian Turkey Subs

Mix together mayo and cheese, then layer all ingredients on the bread.

Mix together mayo and cheese in a medium bowl until well combined. 

Slice french bread or baguette in half lengthwise and spread the cheese mixture over one side. 

On the other side, layer sliced turkey, pepperoni, and onion. 

Baked turkey sub.

Wrap sandwich in aluminum foil and bake at 350 for about 15 to 20 minutes or until toasty and heated through. That’s it!

I hope you get to make my hot turkey sandwich recipe soon. It’s a definite crowd pleaser and with very little effort you have an extremely satisfying meal. One sandwich usually serves about two to three people. 


Because we’re baking the bread, this is one of those recipes you should serve immediately.

Recipe Notes

  • After the sandwich has finished baking, you can add other fresh vegetables to the hoagie, like tomato slices, shredded lettuce, chopped bell pepper, olives, dill pickles, and avocado.
  • For added flavor, add a spread of your favorite mustard (whether that’s yellow mustard or Dijon mustard) to the baguette before adding the cheese mixture.
  • Other delicious types of cheese you can use on your turkey sub include provolone cheese, mozzarella cheese, Swiss cheese, and Monterey Jack cheese.
  • If the pepperoni has too much heat for you and your family, you can use cooked turkey bacon strips instead.
  • To make individual baked turkey subs, use hot dog buns instead.
  • To enhance the Italian flavor, go ahead and sprinkle the hoagie with 2 teaspoons of Italian seasoning or dried basil before baking.
  • This is a great recipe to make with Thanksgiving leftovers if you have leftover turkey in the fridge.

You may also like these other tasty sandwich recipes:

French Dip Sandwiches Recipe (With a Twist)

Classic Reuben Sandwich

Pimento Cheese Sandwich

Steak Sandwiches (World’s Easiest Supper)

Loose Meat Sandwiches

Italian Beef Sandwiches

Italian turkey subs (game day recipes).

Italian Turkey Subs

My turkey subs recipe includes a baked crusty bread sandwich with sharp cheddar cheese, mayo, smoked turkey, onion, and turkey pepperoni.
Prep Time: 10 minutes
Cook Time: 20 minutes
Total Time: 30 minutes
Course: Main Course
Cuisine: American
Keyword: cheese, sandwich, turkey
Servings: 3 people
Calories: 374kcal


  • 1 loaf crusty french bread
  • 2 cups finely shredded sharp cheddar cheese
  • 1/2 cup mayo
  • 5 ounces thinly sliced smoked turkey
  • 20-30 slices turkey pepperoni
  • 1/2 medium onion, thinly sliced


  • Cut the loaf of bread in half lengthwise as if you’re going to make a sandwich.
    1 loaf crusty french bread
  • In a small bowl, stir together the mayo and cheese until well mixed. Spread on one side of the bread.
    2 cups finely shredded sharp cheddar cheese, 1/2 cup mayo
  • On the other side, layer turkey, pepperoni, and onion.
    5 ounces thinly sliced smoked turkey, 20-30 slices turkey pepperoni, 1/2 medium onion, thinly sliced
  • Wrap the sandwich in aluminum foil and bake in a 350-degree oven for 15 to 20 minutes or until the cheese is melted and the sandwich is toasty and heated through.


Calories: 374kcal
Tried this recipe?Mention @southernplate or tag #southernplate!

This post was originally published in 2018 and updated in 2020.

Being happy doesn’t mean that everything is perfect. It means you’ve decided to look beyond the imperfections. 

~ Unknown

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  1. Maybe try it in all small letters?
    I just talked to Southern Breeze and they said : The promo code is still active until June 30th. The code is for first-time purchasers and only can be used once per customer.

  2. The sandwich and tea look so good. I am intrigued with the shape of ice cubes in your tea. Do you have a special icemaker?

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